Pharmacology

Euprotec specialises in assessing the efficacy of your lead and candidate compounds in highly relevant and validated disease models.

Our models are well-suited to the development of multiple classes of agent including small molecules, natural products, peptides, antibodies and other biologics.

We provide a highly bespoke service, customising studies to meet you exact requirements based on the stage of your program and parameters/endpoints of interest.


 

Bacterial Infection

  • Multiple sites of infection (localised and systemic).
  • Gram positive (including Staphylococcus aureus, Streptococcus pneumoniae, and others).
  • Gram negative (including Pseudomonas aeruginosa, Escherichia coli, Acinetobacter baumanii and others).
  • Anaerobes (including Clostridium difficile).

Fungal Infection

  • Multiple sites of infection (localised and systemic).
  • Candida sp., Aspergillus sp., Zygomycetes, Malassezia sp.

 

• Respiratory and Allergy

  • Acute and chronic models of asthma, sensitisation and allergy.
  • Multiple Endpoints including histology, cytology and cytokines.
  • Tissue burden (culture and qPCR), blood culture, biomarkers, histology, toxin (ELISA), and others.
  • Development of new and bespoke models.

 

Euprotec has an excellent track record in the development of new efficacy models. If you require access to a specific model, please contact us to arrange a discussion.

Euprotec - pharmacology services